Structural insights into the potential binding sites of Cathepsin D using molecular modelling techniques

Abstract Alzheimer’s disease (AD) is the most prevalent type of dementia caused by the accumulation of amyloid beta (Aβ) peptides. The extracellular deposition of Aβ peptides in human AD brain causes neuronal death. Therefore, it has been found that Aβ peptide degradation is a possible therapeutic t...

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Bibliographic Details
Main Authors: Subodh A. Kamble, Sagar S. Barale, Ali Abdulmawjood Mohammed, Sneha B. Paymal, Nitin M. Naik, Kailas D. Sonawane
Format: Article
Language:English
Published: Springer 2024-04-01
Series:Amino Acids
Subjects:
Online Access:https://doi.org/10.1007/s00726-023-03367-1
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