Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System
Objective: This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders. Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We mea...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1061_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841543522349481984 |
|---|---|
| author | Priyanka Choudhary Jyoti Kasana Bhupender Bhati Vidyadevi Chandavarkar Deepak Bhargava Mithilesh N. Mishra |
| author_facet | Priyanka Choudhary Jyoti Kasana Bhupender Bhati Vidyadevi Chandavarkar Deepak Bhargava Mithilesh N. Mishra |
| author_sort | Priyanka Choudhary |
| collection | DOAJ |
| description | Objective:
This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders.
Study Design:
The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med).
Results:
Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001).
Conclusion:
Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity. |
| format | Article |
| id | doaj-art-2b7069d610c54cf29365b055c0c6cb24 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-2b7069d610c54cf29365b055c0c6cb242025-01-13T10:03:14ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3524S352710.4103/jpbs.jpbs_1061_24Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis SystemPriyanka ChoudharyJyoti KasanaBhupender BhatiVidyadevi ChandavarkarDeepak BhargavaMithilesh N. MishraObjective: This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders. Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med). Results: Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001). Conclusion: Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity.https://journals.lww.com/10.4103/jpbs.jpbs_1061_24computer-aided image analysiscytomorphologycytomorphometryoral squamessmoking |
| spellingShingle | Priyanka Choudhary Jyoti Kasana Bhupender Bhati Vidyadevi Chandavarkar Deepak Bhargava Mithilesh N. Mishra Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System Journal of Pharmacy and Bioallied Sciences computer-aided image analysis cytomorphology cytomorphometry oral squames smoking |
| title | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
| title_full | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
| title_fullStr | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
| title_full_unstemmed | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
| title_short | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
| title_sort | cytomorphological and cytomorphometric analysis of oral squames in smokers using computer aided image analysis system |
| topic | computer-aided image analysis cytomorphology cytomorphometry oral squames smoking |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1061_24 |
| work_keys_str_mv | AT priyankachoudhary cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem AT jyotikasana cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem AT bhupenderbhati cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem AT vidyadevichandavarkar cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem AT deepakbhargava cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem AT mithileshnmishra cytomorphologicalandcytomorphometricanalysisoforalsquamesinsmokersusingcomputeraidedimageanalysissystem |