NR2F6 as a Disease Driver and Candidate Therapeutic Target in Experimental Cerebral Malaria

NR2F6 as a Disease Driver and Candidate Therapeutic Target in Experimental Cerebral Malaria

Cerebral malaria (CM) is the severe progression of an infection with <i>Plasmodium falciparum</i>, causing detrimental damage to brain tissue and is the most frequent cause of <i>Plasmodium falciparum</i> mortality. The critical role of brain-infiltrating CD8<sup>+</...

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Bibliographic Details
Main Authors: Victoria E. Stefan, Victoria Klepsch, Nikolaus Thuille, Martina Steinlechner, Sebastian Peer, Kerstin Siegmund, Peter Lackner, Erich Schmutzhard, Karin Albrecht-Schgör, Gottfried Baier
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
experimental cerebral malaria (ECM)
compromised blood–brain barrier (BBB) integrity
CD8<sup>+</sup> T cell brain infiltration
nuclear receptor subfamily 2
group F
member 6 (NR2F6)
Online Access:https://www.mdpi.com/2073-4409/14/15/1162
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