Thiadiazole-thiazole derivatives as potent anti-tubercular agents: Synthesis, biological evaluation, and In silico docking studies

Thiadiazole-thiazole derivatives as potent anti-tubercular agents: Synthesis, biological evaluation, and In silico docking studies

The present study focuses on research findings related to the development and assessment of thiadiazole-linked thiazole derivatives as promising anti-tubercular agents. We present the synthesis data of eleven new compounds (4a-4k) and confirm their structures using spectroscopic techniques. Subseque...

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Main Authors: Samin A. Shaikh, Shivaji R. Labhade, Raju R. Kale, Prajakta Y. Pachorkar, Rohan J. Meshram, Kamlesh S. Jain, Hrishikesh S. Labhade, Dipak D. Bhanushali, Rahul A. More, Charushila K. Nerkar, Santosh S. Chobe, Aniket N. Marathe, Satish N. Wakchaure, Deepak R. Boraste
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Anti-tuberculosis
Thiazole
Tetra-n-butylammonium bromide
Thiadiazole
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417424000554
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