Risk factor of severe diarrhea and enterocolitis induced by CAPOX: a retrospective multicenter study

Risk factor of severe diarrhea and enterocolitis induced by CAPOX: a retrospective multicenter study

Background: We have previously suggested that concurrent use of capecitabine plus oxaliplatin (CAPOX) and angiotensin receptor blockers (ARBs) significantly increased the risk of severe diarrhea and/or enterocolitis. We conducted a multicenter larger study to validate this finding, adjusting for oth...

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Main Authors: A. Teixeira, T. Felismino, M.D. Donadio, G. Catani, A.L.M. da Silva, R. Weschenfelder, R.D. Peixoto, J.M. O’Connor, A.K. Coutinho, R.P. Riechelmann
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:ESMO Gastrointestinal Oncology
Subjects:
colorectal cancer
diarrhea
angiotensin receptor blockers
capecitabine
oxaliplatin
Online Access:http://www.sciencedirect.com/science/article/pii/S2949819824000712
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