Identification of a novel disulfidptosis-related gene signature in osteoarthritis using bioinformatics analysis and experimental validation

Identification of a novel disulfidptosis-related gene signature in osteoarthritis using bioinformatics analysis and experimental validation

Abstract Osteoarthritis (OA) is a degenerative bone disease characterized by the destruction of joint cartilage and synovial inflammation, involving intricate immune regulation processes. Disulfidptosis, a novel form of programmed cell death, has recently been identified; however, the effects and ro...

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Bibliographic Details
Main Authors: Mingjie Wei, Xiangwen Shi, Wenbao Tang, Qian Lv, Yipeng Wu, Yongqing Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Osteoarthritis
Disulfidptosis
Chondrocyte
Single-cell sequencing
Diagnosis
Online Access:https://doi.org/10.1038/s41598-025-85569-z
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