Radical SAM cyclophane synthase catalyzes uniform cyclophane formation at multiple Trp-motifs

Cyclophane-containing products from ribosomally synthesized and post-translationally modified peptides (RiPPs) are generated by radical SAM cyclophane synthases (rSAM). In the past few years, rSAM enzymes that catalyze uniform cyclophanes at multiple Trp-motifs on the precursor peptides have been di...

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Bibliographic Details
Main Authors: Abujunaid Habib Khan, Jabal Rahmat Haedar, Anitra Zīle, Chin-Soon Phan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Tetrahedron Chem
Online Access:http://www.sciencedirect.com/science/article/pii/S2666951X25000105
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