p21 regulates the migration and polarization of macrophages in diabetic tooth extraction wound by regulating periodontal ligament fibroblasts

p21 regulates the migration and polarization of macrophages in diabetic tooth extraction wound by regulating periodontal ligament fibroblasts

[Objective:] To explore the expression of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) in the healing process of tooth extraction wounds in diabetic mice and the effect on migration and polarization of macrophages. [Methods:] C57BL/6 male mice were selected to construct a model of diabetes mell...

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Bibliographic Details
Main Authors: ZHU Jiayu, YI Zimei, CHEN Siyi, DING Shuwen, YAN Jiayu, WU Junhua
Format: Article
Language:zho
Published: Editorial Office of Journal of Oral and Maxillofacial Surgery 2025-04-01
Series:Kouqiang hemian waike zazhi
Subjects:
tooth extraction socket
diabetes mellitus
p21
macrophage migration
macrophage polarization
Online Access:https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2025.02.003
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