Pedunculopontine-stimulation obstructs hippocampal theta rhythm and halts movement

Abstract While the movement of rodents can be paused by optogenetic stimulation of a brainstem nucleus, the pedunculopontine nucleus (PPN), it is unknown whether this response has a functional purpose. The arrest appears conspicuously similar to fear-induced freezing behavior and could constitute a...

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Bibliographic Details
Main Authors: Jaspreet Kaur, Salif A. Komi, Oksana Dmytriyeva, Grace A. Houser, Madelaine C. A. Bonfils, Rune W. Berg
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-01695-8
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