Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma
Papillary thyroid carcinomas (PTCs) usually extend to lymph nodes in the neck and mediastinum. Rarely, they invade the neighboring upper airway anatomical structures. We report a 56-year-old woman who presented with symptoms of upper airway obstruction. Imaging studies revealed a lesion derived from...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2013/579527 |
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| author | Nickolaos Pontikides Spyridon Karras Antonios Papagiannis Athina Kaprara Panagiotis Anagnostis George Noussios Argyrios Doumas Apostolos Goropoulos Ioannis Iakovou Georgios Kotronis Konstantinos Bantis Gerasimos Krassas |
| author_facet | Nickolaos Pontikides Spyridon Karras Antonios Papagiannis Athina Kaprara Panagiotis Anagnostis George Noussios Argyrios Doumas Apostolos Goropoulos Ioannis Iakovou Georgios Kotronis Konstantinos Bantis Gerasimos Krassas |
| author_sort | Nickolaos Pontikides |
| collection | DOAJ |
| description | Papillary thyroid carcinomas (PTCs) usually extend to lymph nodes in the neck and mediastinum. Rarely, they invade the neighboring upper airway anatomical structures. We report a 56-year-old woman who presented with symptoms of upper airway obstruction. Imaging studies revealed a lesion derived from the thyroid which invaded and obstructed the trachea, which appeared to be a highly differentiated PTC. Total thyroidectomy was performed, with removal of the endotracheal part of the mass along with the corresponding anterior tracheal rings. Two months later, a whole body I131 scan after recombinant human thyroid-stimulating hormone (rh-TSH) administration was performed and revealed a residual mass in upper left thyroid lobe. Subsequently, 150 mCi I131 were given following rh-TSH administration. Nine months later, there was no sign of residual tumor. This case is the first one reported in the literature regarding rh-TSH administration prior to RAI ablation in a PTC obstructing the trachea. |
| format | Article |
| id | doaj-art-2867739a2f384415a31e4facfd9daf07 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-2867739a2f384415a31e4facfd9daf072025-02-03T05:47:50ZengWileyCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/579527579527Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid CarcinomaNickolaos Pontikides0Spyridon Karras1Antonios Papagiannis2Athina Kaprara3Panagiotis Anagnostis4George Noussios5Argyrios Doumas6Apostolos Goropoulos7Ioannis Iakovou8Georgios Kotronis9Konstantinos Bantis10Gerasimos Krassas11Department of Endocrinology-Diabetes, Panagia General Hospital, 22 Plastira Street, 55132 Thessaloniki, GreeceDepartment of Endocrinology-Diabetes, Panagia General Hospital, 22 Plastira Street, 55132 Thessaloniki, GreecePulmonary Department, St. Luke's Hospital, 55236 Thessaloniki, GreeceDepartment of Endocrinology-Diabetes, Panagia General Hospital, 22 Plastira Street, 55132 Thessaloniki, GreeceDepartment of Endocrinology, Hippokration Hospital of Thessaloniki, 54642 Thessaloniki, GreeceLaboratory of Anatomy Department of Physical Education and Sports Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceThird Department of Nuclear Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, 56429 Thessaloniki, GreeceDepartment of Endocrine Surgery, St. Luke's Hospital, 55236 Thessaloniki, GreeceThird Department of Nuclear Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, 56429 Thessaloniki, Greece3rd Department of Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, 56429 Thessaloniki, Greece3rd Department of Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, 56429 Thessaloniki, GreeceDepartment of Endocrinology-Diabetes, Panagia General Hospital, 22 Plastira Street, 55132 Thessaloniki, GreecePapillary thyroid carcinomas (PTCs) usually extend to lymph nodes in the neck and mediastinum. Rarely, they invade the neighboring upper airway anatomical structures. We report a 56-year-old woman who presented with symptoms of upper airway obstruction. Imaging studies revealed a lesion derived from the thyroid which invaded and obstructed the trachea, which appeared to be a highly differentiated PTC. Total thyroidectomy was performed, with removal of the endotracheal part of the mass along with the corresponding anterior tracheal rings. Two months later, a whole body I131 scan after recombinant human thyroid-stimulating hormone (rh-TSH) administration was performed and revealed a residual mass in upper left thyroid lobe. Subsequently, 150 mCi I131 were given following rh-TSH administration. Nine months later, there was no sign of residual tumor. This case is the first one reported in the literature regarding rh-TSH administration prior to RAI ablation in a PTC obstructing the trachea.http://dx.doi.org/10.1155/2013/579527 |
| spellingShingle | Nickolaos Pontikides Spyridon Karras Antonios Papagiannis Athina Kaprara Panagiotis Anagnostis George Noussios Argyrios Doumas Apostolos Goropoulos Ioannis Iakovou Georgios Kotronis Konstantinos Bantis Gerasimos Krassas Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma Case Reports in Otolaryngology |
| title | Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma |
| title_full | Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma |
| title_fullStr | Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma |
| title_full_unstemmed | Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma |
| title_short | Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Tracheal Obstruction by an Invading Well-Differentiated Thyroid Carcinoma |
| title_sort | recombinant human thyrotropin aided radioiodine therapy in tracheal obstruction by an invading well differentiated thyroid carcinoma |
| url | http://dx.doi.org/10.1155/2013/579527 |
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