Plasma biomarkers identify brain ATN abnormalities in a dementia-free population-based cohort

Plasma biomarkers identify brain ATN abnormalities in a dementia-free population-based cohort

Abstract Introduction Using the ATN framework, we evaluated the potential of plasma biomarkers to identify abnormal brain amyloid-beta (Aβ) positron emission tomography (PET), tau-PET and neurodegeneration in a socioeconomically disadvantaged population-based cohort. Methods Community-dwelling demen...

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Main Authors: Menayit Tamrat Dresse, Pamela C. L. Ferreira, Akshay Prasadan, Jihui L. Diaz, Xuemei Zeng, Bruna Bellaver, Guilherme Povala, Victor L. Villemagne, M. Ilyas Kamboh, Ann D. Cohen, Tharick A. Pascoal, Mary Ganguli, Beth E. Snitz, C. Elizabeth Shaaban, Thomas K. Karikari
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Amyloid beta
Tau pathology
Neurodegeneration
Neuroimaging
ATN framework
P-tau217
Online Access:https://doi.org/10.1186/s13195-025-01803-w
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https://doi.org/10.1186/s13195-025-01803-w

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