Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease

Podocytes are extremely important for maintaining the stability of the glomerular filtration barrier,which can lead to glomerular filtration dysfunction and associated kidney disease.Epithelial-mesenchymal transition(EMT)is a manifestation of podocyte injury and one of the initiating factors of vari...

Full description

Saved in:
Bibliographic Details
Main Authors: CHEN Hai-yun, AO Ying, ZHU Ya-nan, WANG Hui
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2020-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57907317&Fpath=home&index=0
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Podocytes are extremely important for maintaining the stability of the glomerular filtration barrier,which can lead to glomerular filtration dysfunction and associated kidney disease.Epithelial-mesenchymal transition(EMT)is a manifestation of podocyte injury and one of the initiating factors of various glomerular diseases.This article focuses on the definition,specific manifestations,inducing factors,mechanisms of occurrence and related glomerular diseases of the podocyte EMT and its prevention and treatment,in order to clarify the recent research progress of podocyte EMT,and provide reference for the treatment of related kidney diseases.
ISSN:1671-2390