Fisetin attenuates AlCl3-induced neurodegeneration by modulating oxidative stress and inflammatory cytokine release in adult albino wistar rats.

Fisetin attenuates AlCl3-induced neurodegeneration by modulating oxidative stress and inflammatory cytokine release in adult albino wistar rats.

Aim: Natural flavonoids have powerful antioxidant and anti-inflammatory activities against neurodegenerative diseases. Fisetin is a powerful flavonoid that targets a variety of neurological disorders. Aluminum (Al) has been linked to several neurological conditions, such as Parkinsons disease, autis...

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Bibliographic Details
Main Authors: Emeka Anyanwu G, Jacinta Nwachukwu I, Rademene Oria S, Kosisochukwu Obasi K, Precious Ekwueme E, Nto Nto J, Chinyere Anyanwu N
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Flavonoids
Neurodegeneration
Aluminum chloride (AlCl3)
Oxidative stress
Neuroinflammation
Fisetin
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024001951
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http://www.sciencedirect.com/science/article/pii/S2214750024001951

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