Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

Abstract Placental abnormalities are associated with two of the most common and serious complications of human pregnancy, maternal preeclampsia (PE) and fetal intrauterine growth restriction (IUGR), each disorder affecting ∼5% of all pregnancies. An important question for the use of the mouse as a m...

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Bibliographic Details
Main Authors: Brian Cox, Max Kotlyar, Andreas I Evangelou, Vladimir Ignatchenko, Alex Ignatchenko, Kathie Whiteley, Igor Jurisica, S Lee Adamson, Janet Rossant, Thomas Kislinger
Format: Article
Language:English
Published: Springer Nature 2009-06-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2009.37
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