The development of single-domain VHH nanobodies that target the Candida albicans cell surface

The development of single-domain VHH nanobodies that target the Candida albicans cell surface

ABSTRACT Candida albicans causes life-threatening invasive infections that are hard to diagnose and treat, with drug resistance leading to treatment failure. The goal of this study was to develop VHH (single variable domain on a heavy chain) nanobodies to detect drug-resistant infections. Llamas wer...

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Bibliographic Details
Main Authors: Giuseppe Buda De Cesare, Frank M. Sauer, Anna Kolecka, Aimilia A. Stavrou, Theo C. Verrips, Teun Boekhout, Edward Dolk, Carol A. Munro
Format: Article
Language:English
Published: American Society for Microbiology 2024-11-01
Series:Microbiology Spectrum
Subjects:
antibodies
Candida albicans
fungal cell wall
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04269-23
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https://journals.asm.org/doi/10.1128/spectrum.04269-23

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