Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
Anemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on t...
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Termedia Publishing House
2017-12-01
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Series: | Gastroenterology Review |
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author | Edyta Tulewicz-Marti Andrzej Moniuszko Grażyna Rydzewska |
author_facet | Edyta Tulewicz-Marti Andrzej Moniuszko Grażyna Rydzewska |
author_sort | Edyta Tulewicz-Marti |
collection | DOAJ |
description | Anemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on their quality of life, regular screening is recommended. In case of IDA type of medication and route of administration should be determined by many factors such as general condition of the patient, IBD activity or anemia severity. Intravenous iron supplementation is the preferred route but may be associated with phosphate drop or even severe hypophosphatemia (HP). The mechanism of HP related to the intravenous iron infusions is not clearly known yet, but it might be related to the change of FGF-23 levels. What more not all parenteral forms of iron are equal and some may have a higher risk of HP than others. |
format | Article |
id | doaj-art-273df2e9ac9640e3bff70e68b2e7a5c0 |
institution | Kabale University |
issn | 1895-5770 1897-4317 |
language | English |
publishDate | 2017-12-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Gastroenterology Review |
spelling | doaj-art-273df2e9ac9640e3bff70e68b2e7a5c02025-01-10T14:06:17ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172017-12-0112423924310.5114/pg.2017.7209631239Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practiceEdyta Tulewicz-MartiAndrzej MoniuszkoGrażyna RydzewskaAnemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on their quality of life, regular screening is recommended. In case of IDA type of medication and route of administration should be determined by many factors such as general condition of the patient, IBD activity or anemia severity. Intravenous iron supplementation is the preferred route but may be associated with phosphate drop or even severe hypophosphatemia (HP). The mechanism of HP related to the intravenous iron infusions is not clearly known yet, but it might be related to the change of FGF-23 levels. What more not all parenteral forms of iron are equal and some may have a higher risk of HP than others.https://www.termedia.pl/Management-of-anemia-in-inflammatory-bowel-disease-a-challenge-in-everyday-clinical-practice,41,31239,1,1.htmlanemia inflammatory bowel disease hypophosphatemia FGF23 |
spellingShingle | Edyta Tulewicz-Marti Andrzej Moniuszko Grażyna Rydzewska Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice Gastroenterology Review anemia inflammatory bowel disease hypophosphatemia FGF23 |
title | Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice |
title_full | Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice |
title_fullStr | Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice |
title_full_unstemmed | Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice |
title_short | Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice |
title_sort | management of anemia in inflammatory bowel disease a challenge in everyday clinical practice |
topic | anemia inflammatory bowel disease hypophosphatemia FGF23 |
url | https://www.termedia.pl/Management-of-anemia-in-inflammatory-bowel-disease-a-challenge-in-everyday-clinical-practice,41,31239,1,1.html |
work_keys_str_mv | AT edytatulewiczmarti managementofanemiaininflammatoryboweldiseaseachallengeineverydayclinicalpractice AT andrzejmoniuszko managementofanemiaininflammatoryboweldiseaseachallengeineverydayclinicalpractice AT grazynarydzewska managementofanemiaininflammatoryboweldiseaseachallengeineverydayclinicalpractice |