Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice

Anemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on t...

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Main Authors: Edyta Tulewicz-Marti, Andrzej Moniuszko, Grażyna Rydzewska
Format: Article
Language:English
Published: Termedia Publishing House 2017-12-01
Series:Gastroenterology Review
Subjects:
Online Access:https://www.termedia.pl/Management-of-anemia-in-inflammatory-bowel-disease-a-challenge-in-everyday-clinical-practice,41,31239,1,1.html
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author Edyta Tulewicz-Marti
Andrzej Moniuszko
Grażyna Rydzewska
author_facet Edyta Tulewicz-Marti
Andrzej Moniuszko
Grażyna Rydzewska
author_sort Edyta Tulewicz-Marti
collection DOAJ
description Anemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on their quality of life, regular screening is recommended. In case of IDA type of medication and route of administration should be determined by many factors such as general condition of the patient, IBD activity or anemia severity. Intravenous iron supplementation is the preferred route but may be associated with phosphate drop or even severe hypophosphatemia (HP). The mechanism of HP related to the intravenous iron infusions is not clearly known yet, but it might be related to the change of FGF-23 levels. What more not all parenteral forms of iron are equal and some may have a higher risk of HP than others.
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id doaj-art-273df2e9ac9640e3bff70e68b2e7a5c0
institution Kabale University
issn 1895-5770
1897-4317
language English
publishDate 2017-12-01
publisher Termedia Publishing House
record_format Article
series Gastroenterology Review
spelling doaj-art-273df2e9ac9640e3bff70e68b2e7a5c02025-01-10T14:06:17ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172017-12-0112423924310.5114/pg.2017.7209631239Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practiceEdyta Tulewicz-MartiAndrzej MoniuszkoGrażyna RydzewskaAnemia is the most common extraintestinal manifestation and complication of inflammatory bowel disease (IBD). Its etiology is multifactorial and mostly is a combination of iron deficiency anemia (IDA) and chronic anemia (ACD). Because of its high incidence in patients with IBD and its influence on their quality of life, regular screening is recommended. In case of IDA type of medication and route of administration should be determined by many factors such as general condition of the patient, IBD activity or anemia severity. Intravenous iron supplementation is the preferred route but may be associated with phosphate drop or even severe hypophosphatemia (HP). The mechanism of HP related to the intravenous iron infusions is not clearly known yet, but it might be related to the change of FGF-23 levels. What more not all parenteral forms of iron are equal and some may have a higher risk of HP than others.https://www.termedia.pl/Management-of-anemia-in-inflammatory-bowel-disease-a-challenge-in-everyday-clinical-practice,41,31239,1,1.htmlanemia inflammatory bowel disease hypophosphatemia FGF23
spellingShingle Edyta Tulewicz-Marti
Andrzej Moniuszko
Grażyna Rydzewska
Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
Gastroenterology Review
anemia
inflammatory bowel disease
hypophosphatemia
FGF23
title Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
title_full Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
title_fullStr Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
title_full_unstemmed Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
title_short Management of anemia in inflammatory bowel disease: a challenge in everyday clinical practice
title_sort management of anemia in inflammatory bowel disease a challenge in everyday clinical practice
topic anemia
inflammatory bowel disease
hypophosphatemia
FGF23
url https://www.termedia.pl/Management-of-anemia-in-inflammatory-bowel-disease-a-challenge-in-everyday-clinical-practice,41,31239,1,1.html
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AT andrzejmoniuszko managementofanemiaininflammatoryboweldiseaseachallengeineverydayclinicalpractice
AT grazynarydzewska managementofanemiaininflammatoryboweldiseaseachallengeineverydayclinicalpractice