Oral atogepant mitigates spreading depolarization-induced pain and anxiety behavior in mice
Abstract Background Spreading depolarization (SD) is the most likely cause of migraine aura and may be linked to trigeminal nociception. Using minimally invasive optogenetic SD induction (opto-SD), we previously showed that SD triggers acute periorbital mechanical allodynia-like behavior, supporting...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | The Journal of Headache and Pain |
| Online Access: | https://doi.org/10.1186/s10194-025-02125-w |
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