Engineered substrates with imprinted cell-like topographies induce direct differentiation of adipose-derived mesenchymal stem cells into Schwann cells

Engineered substrates with imprinted cell-like topographies induce direct differentiation of adipose-derived mesenchymal stem cells into Schwann cells

Differentiation of stem cells to Schwann is considered efficient way for nerve regeneration since the sources of human Schwann cells are limited for clinical application. It is demonstrated that mimicking micromechanical forces or micro/nanotopographical environments that stem cells are experienced...

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Bibliographic Details
Main Authors: Mehrdad Moosazadeh Moghaddam, Shahin Bonakdar, Mohammad Ali Shokrgozar, Arash Zaminy, Hojatollah Vali, Shahab Faghihi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Mesenchymal stem cell
Schwann cell
cell-like topography
imprinted substrate
direct differentiation
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1586718
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https://www.tandfonline.com/doi/10.1080/21691401.2019.1586718

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