Outer membrane permeability of mcr-positive bacteria reveals potent synergy of colistin and macromolecular antibiotics against colistin-resistant Acinetobacter baumannii

Outer membrane permeability of mcr-positive bacteria reveals potent synergy of colistin and macromolecular antibiotics against colistin-resistant Acinetobacter baumannii

Colistin (CT) is the last-resort of antibiotic against multidrug-resistance (MDR) Acinetobacter baumannii (A. baumannii) infection. However, colistin resistance is increasingly reported in A. baumannii isolates partially due to the global emergence and dissemination of plasmid-borne mobile colistin...

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Bibliographic Details
Main Authors: Meisong Li, Furong Ma, Hui Zhao, Dianrong Zhou, Lujie Liang, Runling Lv, Jiachen Li, Yaxuan Wang, Lin Xu, Chenfei Liu, Guo-Bao Tian, Siyuan Feng, Yong Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Microbiology
Subjects:
Acinetobacter baumannii
colistin
rifampicin
MCR
outer membrane permeability
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1468682/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1468682/full

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