PRRSV evades innate immune cGAS-STING antiviral function via its Nsp5 to deter STING translocation and activation

PRRSV evades innate immune cGAS-STING antiviral function via its Nsp5 to deter STING translocation and activation

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is an important pathogen that seriously endangers pig breeding, causing significant economic losses to the global swine industry. Our previous study found that the DNA sensing innate cGAS-STING signaling pathway plays an important role in i...

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Bibliographic Details
Main Authors: Yulin Xu, Chenglin Chi, Qihang Xin, Jiang Yu, Yuyu Zhang, Pingping Zhang, Wangli Zheng, Sen Jiang, Wanglong Zheng, Nanhua Chen, Jiaqiang Wu, Jianzhong Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
PRRSV
Nsp5
STING
immune evasion
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2548625
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https://www.tandfonline.com/doi/10.1080/21505594.2025.2548625

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