METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION
Results of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». Th...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/301 |
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| _version_ | 1849243880753463296 |
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| author | N. N. Krylov E. V. Kompantseva |
| author_facet | N. N. Krylov E. V. Kompantseva |
| author_sort | N. N. Krylov |
| collection | DOAJ |
| description | Results of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». The assay method for the sum of flavonoids in the dry extracts from this raw material and tablets «Ginkgotropil-forte» is developed. Justification of limit of flavonoid content in tablets «Ginkgotropil-forte» is presented and the limit is not less than 6 mg, based on the average weight of the tablet. The proposed method was validated for specificity, linearity, precision and accuracy. |
| format | Article |
| id | doaj-art-264a36e3e50f4d13aa93e687e9dc4b1a |
| institution | Kabale University |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-264a36e3e50f4d13aa93e687e9dc4b1a2025-08-20T03:59:20ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0103146151301METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTIONN. N. Krylov0E. V. Kompantseva1Pyatigorsk Medical and Pharmaceutical Institute - a branch of SEI HPE Volgograd State Medical University, Russian Ministry of HealthPyatigorsk Medical and Pharmaceutical Institute - a branch of SEI HPE Volgograd State Medical University, Russian Ministry of HealthResults of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». The assay method for the sum of flavonoids in the dry extracts from this raw material and tablets «Ginkgotropil-forte» is developed. Justification of limit of flavonoid content in tablets «Ginkgotropil-forte» is presented and the limit is not less than 6 mg, based on the average weight of the tablet. The proposed method was validated for specificity, linearity, precision and accuracy.https://www.pharmjournal.ru/jour/article/view/301tabletsflavonoidsginkgo bilobameadowsweetvalidationdifferential spectrophotometry |
| spellingShingle | N. N. Krylov E. V. Kompantseva METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION Разработка и регистрация лекарственных средств tablets flavonoids ginkgo biloba meadowsweet validation differential spectrophotometry |
| title | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_full | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_fullStr | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_full_unstemmed | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_short | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_sort | method development and validation of total flavonoids assay in tablets with nootropic action |
| topic | tablets flavonoids ginkgo biloba meadowsweet validation differential spectrophotometry |
| url | https://www.pharmjournal.ru/jour/article/view/301 |
| work_keys_str_mv | AT nnkrylov methoddevelopmentandvalidationoftotalflavonoidsassayintabletswithnootropicaction AT evkompantseva methoddevelopmentandvalidationoftotalflavonoidsassayintabletswithnootropicaction |