RnaXtract, a tool for extracting gene expression, variants, and cell-type composition from bulk RNA sequencing

RnaXtract, a tool for extracting gene expression, variants, and cell-type composition from bulk RNA sequencing

Abstract RNA sequencing (RNA-seq) is a widely used method in transcriptomics research, offering insights into gene expression, variant discovery, and, when deconvoluted, the cellular composition of complex tissues. However, existing RNA-seq pipelines frequently emphasize gene expression analysis and...

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Bibliographic Details
Main Authors: Sophiane G. Bouirdene, Simon Gotty, Mickaël Leclercq, Charles Joly-Beauparlant, Emeric Texeraud, Steve Bilodeau, Arnaud Droit
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Bulk RNA-seq
Transcriptomics
Snakemake pipeline
Gene expression
Variant calling
Cell deconvolution
Online Access:https://doi.org/10.1038/s41598-025-16875-9
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https://doi.org/10.1038/s41598-025-16875-9

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