A comparison of two MALDI-TOF MS based assays for the detection of carbapenemases in Enterobacterales

A comparison of two MALDI-TOF MS based assays for the detection of carbapenemases in Enterobacterales

Abstract Carbapenem resistant (CRE) and carbapenemase producing Enterobacterales (CPE) in particular, represent a major threat for healthcare systems worldwide. Rapid, reliable, and easy to perform assays are required to enable targeted and effective therapy. MALDI-TOF MS based carbapenemase diagnos...

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Bibliographic Details
Main Authors: Christine Uitz, Josefa Luxner, Simone Friedl, Eva Leitner, Andrea Grisold, Gernot Zarfel, Ivo Steinmetz, Karl Dichtl
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
MALDI-TOF MS
Carbapenemase
Enterobacterales
Mass spectrometry
STAR-Carba
Resistance testing
Online Access:https://doi.org/10.1038/s41598-024-77952-z
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https://doi.org/10.1038/s41598-024-77952-z

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