Design of linear and cyclic peptide binders from protein sequence information

Abstract Structure prediction technology has transformed protein design, yet key challenges remain, particularly in designing novel functions. Many proteins function through interactions with other proteins, making the rational design of these interactions a central problem. While most efforts focus...

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Bibliographic Details
Main Authors: Qiuzhen Li, Efstathios Nikolaos Vlachos, Patrick Bryant
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01601-3
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