Modelling of Cetylpyridinium Chloride Availability in Complex Mixtures for the Prediction of Anti-Microbial Activity Using Diffusion Ordered Spectroscopy, Saturation Transfer Difference and 1D NMR

Modelling of Cetylpyridinium Chloride Availability in Complex Mixtures for the Prediction of Anti-Microbial Activity Using Diffusion Ordered Spectroscopy, Saturation Transfer Difference and 1D NMR

<b>Background/Objectives:</b> A range of NMR techniques, including diffusion ordered spectroscopy (DOSY) were used to characterise complex micelles formed by the anti-microbial cationic surfactant cetylpyridium chloride and to quantify the degree of interaction between cetylpyridium chlo...

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Main Authors: Cameron Robertson, Sayoni Batabyal, Darren Whitworth, Tomris Coban, Angharad Smith, Alessandra Montesanto, Robert Lucas, Adam Le Gresley
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
NMR
formulation
anti-microbial
micelles
diffusion
cetylpyridinium chloride
Online Access:https://www.mdpi.com/1424-8247/17/12/1570
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