Synthesis of Enantiostructured Triacylglycerols Possessing a Saturated Fatty Acid, a Polyunsaturated Fatty Acid and an Active Drug Intended as Novel Prodrugs

Synthesis of Enantiostructured Triacylglycerols Possessing a Saturated Fatty Acid, a Polyunsaturated Fatty Acid and an Active Drug Intended as Novel Prodrugs

This report describes the asymmetric synthesis of a focused library of enantiopure structured triacylglycerols (TAGs) comprised of a single saturated fatty acid (C6, C8, C10, C12, C14 or C16), a pure bioactive n-3 polyunsaturated fatty acid (EPA or DHA) and a potent drug (ibuprofen or naproxen) inte...

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Bibliographic Details
Main Authors: Lena Rós Jónsdóttir, Gudmundur G. Haraldsson
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
asymmetric synthesis
enantiostructured triacylglycerols
lipase
n-3 PUFAs
acylglycerol prodrugs
Online Access:https://www.mdpi.com/1420-3049/29/23/5745
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