DiffCoRank: a comprehensive framework for discovering hub genes and differential gene co-expression in brain implant-associated tissue responses

DiffCoRank: a comprehensive framework for discovering hub genes and differential gene co-expression in brain implant-associated tissue responses

Abstract Background Brain implants have significant potential for therapeutic applications and neuroscience research, but complex tissue responses often compromise their long-term stability. To address this challenge, differential coexpression analysis can be used to identify key molecular regulator...

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Bibliographic Details
Main Authors: Anirban Chakraborty, Erin K. Purcell, Michael G. Moore
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Bioinformatics
Subjects:
Differential co-expression analysis
UMAP
DBSCAN
Hub gene
Neural implants
RNA-Seq
Online Access:https://doi.org/10.1186/s12859-025-06232-y
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https://doi.org/10.1186/s12859-025-06232-y

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