Regulatory T cells and matrix-producing cancer associated fibroblasts contribute on the immune resistance and progression of prognosis related tumor subtypes in ccRCC

Regulatory T cells and matrix-producing cancer associated fibroblasts contribute on the immune resistance and progression of prognosis related tumor subtypes in ccRCC

Abstract Clear cell renal cell carcinoma (ccRCC) is a prevalent malignant tumor in the field of urology. The effect of cell heterogeneity on the prognosis and reaction to treatment of ccRCC in large populations is still unclear. By analyzing public single cell RNA-sequencing and bulk RNA-sequencing...

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Bibliographic Details
Main Authors: Chao Zhang, Yisu Song, Xiaobo Cui, Yina Wang, Jiang Liu, Zhouji Shen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Scissor
Machine learning
Multi-omics
Clear cell renal carcinoma
Online Access:https://doi.org/10.1038/s41598-025-06051-4
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https://doi.org/10.1038/s41598-025-06051-4

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