The efficacy and safety of intrawound vancomycin powder to prevent surgical site infection in adult scoliosis surgery (Vanco-SSIASS): study protocol for a prospective, randomized controlled, assessor‑blinded, open‑label, multicenter trial

The efficacy and safety of intrawound vancomycin powder to prevent surgical site infection in adult scoliosis surgery (Vanco-SSIASS): study protocol for a prospective, randomized controlled, assessor‑blinded, open‑label, multicenter trial

Abstract Background Postoperative surgical site infections (SSIs) following adult scoliosis deformity (ASD) correction surgery are receiving more attention globally. Intrawound vancomycin powder in spinal surgical wounds has emerged as a promising strategy to prevent SSIs in recent years. However, t...

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Bibliographic Details
Main Authors: Bo Han, Yong Hai, Yihan Yang, Weishi Liang, Yan Yu, Tao Guo, Duan Sun, Zhangfu Li, Shuilian Chu, Peng Yin
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Trials
Subjects:
Adult scoliosis deformity (ASD)
Surgical site infections (SSIs)
Vancomycin
Intrawound
Efficacy
Safety
Online Access:https://doi.org/10.1186/s13063-025-09000-8
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https://doi.org/10.1186/s13063-025-09000-8

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