A high-resolution two-step evolution experiment in yeast reveals a shift from pleiotropic to modular adaptation.

Evolution by natural selection is expected to be a slow and gradual process. In particular, the mutations that drive evolution are predicted to be small and modular, incrementally improving a small number of traits. However, adaptive mutations identified early in microbial evolution experiments, can...

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Bibliographic Details
Main Authors: Grant Kinsler, Yuping Li, Gavin Sherlock, Dmitri A Petrov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002848
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