Ionotropic purinergic receptor 7 (P2X7) channel structure and pharmacology provides insight regarding non-nucleotide agonism

P2X7 is a member of the Ionotropic Purinergic Receptor (P2X) family. The P2X family of receptors is composed of seven (P2X1–7), ligand-gated, nonselective cation channels. Changes in P2X expression have been reported in multiple disease models. P2Xs have large complex extracellular domains that func...

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Bibliographic Details
Main Authors: Rua’a Al-Aqtash, Daniel M. Collier
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2024.2355150
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