Unveiling the immunopharmacological mechanisms of Danggui Yinzi (DGYZ) in treating chronic urticaria: insights from network pharmacology and experimental validation

Abstract Background Chronic urticaria (CU), a prevalent and often debilitating allergic skin disorder, is primarily triggered by mast cell degranulation. Danggui Yinzi (DGYZ), a traditional Chinese medicine formula, has been employed to treat pruritic conditions. However, the molecular mechanisms un...

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Bibliographic Details
Main Authors: Xu-rui Wang, An-jing Chen, Chang-cheng Hou, Yue-yue Wang, Jing Guo, Ming-yue Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Chinese Medicine
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Online Access:https://doi.org/10.1186/s13020-025-01137-7
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