Progress in animal models for studying hyperuricemia

Progress in animal models for studying hyperuricemia

Hyperuricemia (HUA) is a prevalent metabolic disorder driven by dysregulated purine metabolism and impaired urate excretion, and robust animal models are critical for elucidating its pathophysiology and guiding therapy development. This review systematically examines chemically induced, gene‐edited,...

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Bibliographic Details
Main Authors: Senyue Zhang, Kaiqing Li, Hu Zhang, Tong Fu, Yanchun Ma, Shuxiang Zhang, Guoli Xing, Ying Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
hyperuricemia
animal models
modeling method
gene editing
evaluation indicators
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1636205/full
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