Tofacitinib Safety and Effectiveness in Canadian Patients with Rheumatoid Arthritis by Cardiovascular Risk Enrichment: Subanalysis of the CANTORAL Study

Tofacitinib Safety and Effectiveness in Canadian Patients with Rheumatoid Arthritis by Cardiovascular Risk Enrichment: Subanalysis of the CANTORAL Study

Abstract Introduction ORAL Surveillance, a post-authorisation safety study of patients with rheumatoid arthritis (RA) enriched for cardiovascular (CV) risk, demonstrated increased risk of major adverse CV events (MACE) and malignancies (excluding non-melanoma skin cancer [NMSC]) for tofacitinib vers...

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Main Authors: Boulos Haraoui, Majed Khraishi, Denis Choquette, Isabelle Fortin, Cassandra D. Kinch, Corina Galos, Patrice Roy, David Gruben, Julie Vaillancourt, John S. Sampalis, Edward C. Keystone
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-11-01
Series:Rheumatology and Therapy
Subjects:
Antirheumatic agents
Cardiovascular diseases
JAK inhibitors
Rheumatoid arthritis
Therapeutics
Tofacitinib
Online Access:https://doi.org/10.1007/s40744-024-00719-5
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https://doi.org/10.1007/s40744-024-00719-5

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