Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomyelitis pathogenesis

Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomyelitis pathogenesis

Multiple Sclerosis (MS) is an autoimmune and chronic disease in the brain and spinal cord. MS has inflammatory progression characterized by its hallmark inflammatory plaques. The histological and clinical characteristics of MS are shared by Experimental Autoimmune Encephalomyelitis (EAE). Genetic an...

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Bibliographic Details
Main Authors: Shamrat Kumar Paul, Md Saddam, Nisat Tabassum, Mahbub Hasan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Experimental autoimmune encephalomyelitis
PSMB8
Molecular dynamics simulation
GROMACS essential dynamic analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024171976
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