Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study

Abstract Objective Transcatheter aortic valve replacement (TAVR) is a well-established technique for the treatment of aortic stenosis (AS). However, due to the complex anatomical features of the aortic root, the risk of vascular injury caused by operation under the condition of anatomical variations...

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Main Authors: Yang Chen, Baihua Sun, Zhongyu Wang, Moyang Wang, Hongliang Zhang, Guannan Niu, Zhenyan Zhao, Dejing Feng, Pinghai Zhang, Zhibo Jiang, Junhua Yuan, Junxian Song, Yongjian Wu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Medical Imaging
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Online Access:https://doi.org/10.1186/s12880-025-01867-y
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author Yang Chen
Baihua Sun
Zhongyu Wang
Moyang Wang
Hongliang Zhang
Guannan Niu
Zhenyan Zhao
Dejing Feng
Pinghai Zhang
Zhibo Jiang
Junhua Yuan
Junxian Song
Yongjian Wu
author_facet Yang Chen
Baihua Sun
Zhongyu Wang
Moyang Wang
Hongliang Zhang
Guannan Niu
Zhenyan Zhao
Dejing Feng
Pinghai Zhang
Zhibo Jiang
Junhua Yuan
Junxian Song
Yongjian Wu
author_sort Yang Chen
collection DOAJ
description Abstract Objective Transcatheter aortic valve replacement (TAVR) is a well-established technique for the treatment of aortic stenosis (AS). However, due to the complex anatomical features of the aortic root, the risk of vascular injury caused by operation under the condition of anatomical variations of the aortic root is high, and there is a lack of studies on the anatomical features of the aortic root on CT before TAVR. Therefore, this study will preliminarily summarize anatomical features of aortic root in patients with aortic stenosis treated by TAVR. Methods A retrospective study was conducted at a single center, involving 60 patients with symptomatic severe AS treated TAVR between September 2022 and December 2022. Baseline patient information, CT measurements of aortic root anatomical characteristics, and associated risks were analyzed. Results The mean age of the 60 patients was 77.72 ± 4.33 years, with 39 males (65.00%). The left ventricular ejection fraction was 65.46 ± 13.92%. Valve morphology included 38 cases (63.30%) of tricuspid valves and 22 cases (36.70%) of bicuspid valves. Common anatomical risks identified were acute aortic arch (18.33%), a short ascending aorta (10.00%, 8.33%, 16.67%, 15.00%), ascending aortic dilation (3.33%), a transverse heart (28.33%), cardiac anteversion (68.33%), a short left ventricle (5.00%), and a small left ventricle (5.00%). Conclusion Preoperative cardiac CT scans detect aortic root morphological angle abnormalities in TAVR patients. Angular dimensions of the aortic root show considerable variability among patients, which may have procedural implications for TAVR.
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spelling doaj-art-20d72a2a671149be8ed0d1e8ffeffece2025-08-20T04:02:44ZengBMCBMC Medical Imaging1471-23422025-08-012511910.1186/s12880-025-01867-yAnatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational studyYang Chen0Baihua Sun1Zhongyu Wang2Moyang Wang3Hongliang Zhang4Guannan Niu5Zhenyan Zhao6Dejing Feng7Pinghai Zhang8Zhibo Jiang9Junhua Yuan10Junxian Song11Yongjian Wu12Coronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Radiology, Linyi People’s HospitalDepartment of Medicine, Qingdao UniversityCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeShanghai MicroPort CardioFlow Medtech Co., LtdShanghai MicroPort CardioFlow Medtech Co., LtdDepartment of Special Medicine, School of Basic Medicine, Qingdao UniversityDepartment of Cardiology, Peking University People’s HospitalCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeAbstract Objective Transcatheter aortic valve replacement (TAVR) is a well-established technique for the treatment of aortic stenosis (AS). However, due to the complex anatomical features of the aortic root, the risk of vascular injury caused by operation under the condition of anatomical variations of the aortic root is high, and there is a lack of studies on the anatomical features of the aortic root on CT before TAVR. Therefore, this study will preliminarily summarize anatomical features of aortic root in patients with aortic stenosis treated by TAVR. Methods A retrospective study was conducted at a single center, involving 60 patients with symptomatic severe AS treated TAVR between September 2022 and December 2022. Baseline patient information, CT measurements of aortic root anatomical characteristics, and associated risks were analyzed. Results The mean age of the 60 patients was 77.72 ± 4.33 years, with 39 males (65.00%). The left ventricular ejection fraction was 65.46 ± 13.92%. Valve morphology included 38 cases (63.30%) of tricuspid valves and 22 cases (36.70%) of bicuspid valves. Common anatomical risks identified were acute aortic arch (18.33%), a short ascending aorta (10.00%, 8.33%, 16.67%, 15.00%), ascending aortic dilation (3.33%), a transverse heart (28.33%), cardiac anteversion (68.33%), a short left ventricle (5.00%), and a small left ventricle (5.00%). Conclusion Preoperative cardiac CT scans detect aortic root morphological angle abnormalities in TAVR patients. Angular dimensions of the aortic root show considerable variability among patients, which may have procedural implications for TAVR.https://doi.org/10.1186/s12880-025-01867-yAortic valve stenosisTranscatheter aortic valve replacementAortic root characteristics
spellingShingle Yang Chen
Baihua Sun
Zhongyu Wang
Moyang Wang
Hongliang Zhang
Guannan Niu
Zhenyan Zhao
Dejing Feng
Pinghai Zhang
Zhibo Jiang
Junhua Yuan
Junxian Song
Yongjian Wu
Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
BMC Medical Imaging
Aortic valve stenosis
Transcatheter aortic valve replacement
Aortic root characteristics
title Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
title_full Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
title_fullStr Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
title_full_unstemmed Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
title_short Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study
title_sort anatomical features of aortic root in patients with aortic stenosis treated by tavr an observational study
topic Aortic valve stenosis
Transcatheter aortic valve replacement
Aortic root characteristics
url https://doi.org/10.1186/s12880-025-01867-y
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