Longitudinal network changes and phenoconversion risk in isolated REM sleep behavior disorder

Longitudinal network changes and phenoconversion risk in isolated REM sleep behavior disorder

Abstract Isolated rapid eye movement sleep behavior disorder is a prodrome of α-synucleinopathies. Using positron emission tomography, we assessed changes in Parkinson’s disease-related motor and cognitive metabolic networks and caudate/putamen dopaminergic input in a 4-year longitudinal imaging stu...

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Main Authors: Chris C. Tang, Yoshikazu Nakano, An Vo, Nha Nguyen, Katharina A. Schindlbeck, Paul J. Mattis, Kathleen L. Poston, Jean-François Gagnon, Ronald B. Postuma, Martin Niethammer, Yilong Ma, Shichun Peng, Vijay Dhawan, David Eidelberg
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54695-z
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