High-resolution fecal pharmacokinetic modeling in mice with orally administered antibiotics

High-resolution fecal pharmacokinetic modeling in mice with orally administered antibiotics

Abstract High-resolution fecal pharmacokinetics are crucial for optimizing therapeutic design and evaluating gastrointestinal motility. However, empirical studies with detailed fecal concentration over time data remain limited. This study aims to characterize fecal pharmacokinetics through high-freq...

Full description

Saved in:
Bibliographic Details
Main Authors: Rie Maskawa, Lena Takayasu, Hideki Takayasu, Keiji Watanabe, Shusuke Takemine, Takashi Kakimoto, Kozue Takeshita, Seiko Narushima, Wataru Suda, Misako Takayasu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Pharmacokinetics
Compartment model
Antibiotics
Solid phase extraction
Online Access:https://doi.org/10.1038/s41598-025-10293-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-10293-7

Similar Items