Chemical Space Exploration and Machine Learning-Based Screening of PDE7A Inhibitors

<b>Background/Objectives</b>: Phosphodiesterase 7 (PDE7), a member of the PDE superfamily, selectively catalyzes the hydrolysis of cyclic adenosine 3′,5′-monophosphate (cAMP), thereby regulating the intracellular levels of this second messenger and influencing various physiological funct...

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Bibliographic Details
Main Authors: Yuze Li, Zhe Wang, Shengyao Ma, Xiaowen Tang, Hanting Zhang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
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Online Access:https://www.mdpi.com/1424-8247/18/4/444
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