Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Abstract Polymorphic microbiomes play important roles in colorectal cancer (CRC) occurrence and development. In particular, Fusobacterium nucleatum (F. nucleatum) is prevalent in patients with CRC, and eliminating it is beneficial for treatment. Here, multiple metagenomic sequencing cohorts are comb...

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Main Authors: Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Advanced Science
Subjects:
colorectal cancer
fusobacterium nucleatum
lipid metabolism
metabolic network reconstruction
synthetic microbial community
Online Access:https://doi.org/10.1002/advs.202414232
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https://doi.org/10.1002/advs.202414232

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