Updates on Chimeric Antigen Receptor T-Cells in Large B-Cell Lymphoma

Updates on Chimeric Antigen Receptor T-Cells in Large B-Cell Lymphoma

CD19-targeting chimeric antigen receptor (CAR) T-cells have changed the treatment paradigm of patients with large B-cell lymphoma (LBCL). Three CAR T-cells were approved by the Food and Drug Administration (FDA) for patients with relapsed and/or refractory (R/R) LBCL in the third-line setting: tisag...

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Bibliographic Details
Main Authors: Khalil Saleh, Nadine Khalife, Ahmadreza Arbab, Rita Khoury, Claude Chahine, Rebecca Ibrahim, Zamzam Tikriti, Nohad Masri, Mohamad Hachem, Axel Le Cesne
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
CD19-targeting CAR T-cells
lisocabtagene maraleucel
axicabtagene ciloleucel
tisagenlecleucel
large B-cell lymphoma
Online Access:https://www.mdpi.com/2227-9059/12/12/2810
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