Characteristics of exposure to radioactive iodine during a nuclear incident

During a nuclear accident, numerous products of nuclear fission are released, including isotopes of radioactive iodine. Among them is iodine-131, with a half-life of 8.02 days, which emits β radiation. For decades, it has been effectively and safely used in medicine. However, in the event of a nucle...

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Main Authors: Zaletel Katja, Mihovec Anamarija, Gaberscek Simona
Format: Article
Language:English
Published: Sciendo 2024-10-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2024-0051
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author Zaletel Katja
Mihovec Anamarija
Gaberscek Simona
author_facet Zaletel Katja
Mihovec Anamarija
Gaberscek Simona
author_sort Zaletel Katja
collection DOAJ
description During a nuclear accident, numerous products of nuclear fission are released, including isotopes of radioactive iodine. Among them is iodine-131, with a half-life of 8.02 days, which emits β radiation. For decades, it has been effectively and safely used in medicine. However, in the event of a nuclear accident, uncontrolled exposure can have harmful biological effects. The main sources of internal contamination with iodine-131 are contaminated air, food and water. The most exposed organ is the thyroid gland, where radioactive iodine accumulates via the Na+/I− symporter (NIS). NIS does not distinguish between radioactive iodine isotopes and the stable isotope iodine-127, which is essential for the synthesis of thyroid hormones. Exposure to radioactive iodine during a nuclear accident is primarily associated with papillary thyroid cancer, whose incidence begins to increase a few years after exposure. Children and adolescents are at the highest risk, and the risk is particularly significant for individuals living in iodine-deficient areas.
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spelling doaj-art-1f648ad780a2478d9b329cfb7a62705f2025-01-07T07:56:43ZengSciendoRadiology and Oncology1581-32072024-10-0158445946810.2478/raon-2024-0051Characteristics of exposure to radioactive iodine during a nuclear incidentZaletel Katja0Mihovec Anamarija1Gaberscek Simona2Division of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaDivision of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, SloveniaDuring a nuclear accident, numerous products of nuclear fission are released, including isotopes of radioactive iodine. Among them is iodine-131, with a half-life of 8.02 days, which emits β radiation. For decades, it has been effectively and safely used in medicine. However, in the event of a nuclear accident, uncontrolled exposure can have harmful biological effects. The main sources of internal contamination with iodine-131 are contaminated air, food and water. The most exposed organ is the thyroid gland, where radioactive iodine accumulates via the Na+/I− symporter (NIS). NIS does not distinguish between radioactive iodine isotopes and the stable isotope iodine-127, which is essential for the synthesis of thyroid hormones. Exposure to radioactive iodine during a nuclear accident is primarily associated with papillary thyroid cancer, whose incidence begins to increase a few years after exposure. Children and adolescents are at the highest risk, and the risk is particularly significant for individuals living in iodine-deficient areas.https://doi.org/10.2478/raon-2024-0051thyroidradioactive iodinenuclear accidentthyroid cancerpotassium iodide
spellingShingle Zaletel Katja
Mihovec Anamarija
Gaberscek Simona
Characteristics of exposure to radioactive iodine during a nuclear incident
Radiology and Oncology
thyroid
radioactive iodine
nuclear accident
thyroid cancer
potassium iodide
title Characteristics of exposure to radioactive iodine during a nuclear incident
title_full Characteristics of exposure to radioactive iodine during a nuclear incident
title_fullStr Characteristics of exposure to radioactive iodine during a nuclear incident
title_full_unstemmed Characteristics of exposure to radioactive iodine during a nuclear incident
title_short Characteristics of exposure to radioactive iodine during a nuclear incident
title_sort characteristics of exposure to radioactive iodine during a nuclear incident
topic thyroid
radioactive iodine
nuclear accident
thyroid cancer
potassium iodide
url https://doi.org/10.2478/raon-2024-0051
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AT mihovecanamarija characteristicsofexposuretoradioactiveiodineduringanuclearincident
AT gabersceksimona characteristicsofexposuretoradioactiveiodineduringanuclearincident