DNA aptamer AptERA 2 targets ERA from Staphylococcus aureus and limits GTP hydrolysis

DNA aptamer AptERA 2 targets ERA from Staphylococcus aureus and limits GTP hydrolysis

Abstract Ribosome assembly is a multistep process that ensures a functional ribosome structure. The molecular mechanism that ribosome­associated GTPases (RA­GTPases) use to enhance ribosome assembly accuracy remains largely to be elucidated. Here, we use systematic evolution of ligands by exponentia...

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Bibliographic Details
Main Authors: Katherin Peñaranda, Nicolle Pereira, Orestis Savva, Dezemona Petrelli, Roberto Spurio, Rebecca M. Corrigan, Pohl Milon
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Ribosome assembly
Aptamer
ERA
GTPase
SELEX
Online Access:https://doi.org/10.1038/s41598-025-15180-9
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https://doi.org/10.1038/s41598-025-15180-9

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