Gene editing and CRISPR-dependent homology-mediated end joining
Abstract Gene editing is the intentional modification of a genetic locus in a living cell and is used for two general applications of great importance and wide interest. One is the inactivation of genes (‘knockouts’), a process utilized to delineate the loss-of-function phenotype(s) of a particular...
Saved in:
| Main Authors: | Brian L. Ruis, Anja K. Bielinsky, Eric A. Hendrickson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-025-01442-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells
by: Mariia Mikhova, et al.
Published: (2024-11-01) -
CRISPR Gene Editing in Strawberry
by: Seonghee Lee, et al.
Published: (2018-02-01) -
CRISPR Gene Editing in Strawberry
by: Seonghee Lee, et al.
Published: (2018-02-01) -
PIPKIγ promotes non-homologous end joining through LIG4 to enhance radiotherapy resistance in triple-negative breast cancer
by: Wenge Dong, et al.
Published: (2025-07-01) -
Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing
by: Joseph Hawksworth, et al.
Published: (2018-04-01)