Intratumoral CD3+ T-Lymphocytes Immunoexpression and Its Association with c-Kit, Angiogenesis, and Overall Survival in Malignant Canine Mammary Tumors

In this study 80 malignant CMT were submitted to immunohistochemical detection of CD3, c-kit, VEGF, and CD31, together with clinicopathological parameters of tumor aggressiveness. CD3+ T-cells and c-kit overexpression revealed a positive correlation with VEGF (r = 0.503, P < 0.0001; r = 0.284, P...

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Bibliographic Details
Main Authors: Maria Isabel Carvalho, Isabel Pires, Marlene Dias, Justina Prada, Hugo Gregório, Luis Lobo, Felisbina Queiroga
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2015/920409
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