ACTIVIN RECEPTOR LIGAND FOR THR TREATMENT OF BETA-THALASSEMIA: a SERENDIPITOUS DISCOVERY

b-thalassemia is a hereditary disorder caused by defective production of b-globin chains of hemoglobin (Hb) that leads to an increased a/b globins ratio with subsequent free a-globins. Alpha globin excess causes oxidative stress, RBCs membrane damage, premature death of late-stage erythroid precurso...

Full description

Saved in:
Bibliographic Details
Main Authors: Irene Motta, Valentina Brancaleoni, Isabella Nava, Paola Delbini, Lorena Duca
Format: Article
Language:English
Published: PAGEPress Publications 2020-10-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/4358
Tags: Add Tag
No Tags, Be the first to tag this record!