Endothelial Notch signaling controls insulin transport in muscle

Endothelial Notch signaling controls insulin transport in muscle

Abstract The role of the endothelium is not just limited to acting as an inert barrier for facilitating blood transport. Endothelial cells (ECs), through expression of a repertoire of angiocrine molecules, regulate metabolic demands in an organ‐specific manner. Insulin flux across the endothelium to...

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Main Authors: Sana S Hasan, Markus Jabs, Jacqueline Taylor, Lena Wiedmann, Thomas Leibing, Viola Nordström, Giuseppina Federico, Leticia P Roma, Christopher Carlein, Gretchen Wolff, Bilgen Ekim‐Üstünel, Maik Brune, Iris Moll, Fabian Tetzlaff, Hermann‐Josef Gröne, Thomas Fleming, Cyrill Géraud, Stephan Herzig, Peter P Nawroth, Andreas Fischer
Format: Article
Language:English
Published: Springer Nature 2020-03-01
Series:EMBO Molecular Medicine
Subjects:
caveolae
endothelial cell
insulin transport
muscle
Notch signaling
Online Access:https://doi.org/10.15252/emmm.201809271
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https://doi.org/10.15252/emmm.201809271

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