Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review
One of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation. The presence of risk factors for hyperglycemia or hypertension can result in endothelial nitric oxide (eNOS) dysfunction, thereby c...
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EDP Sciences
2024-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_01006.pdf |
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| author | Capritasari Rafiastiana Akrom Setianto Arif Budi |
| author_facet | Capritasari Rafiastiana Akrom Setianto Arif Budi |
| author_sort | Capritasari Rafiastiana |
| collection | DOAJ |
| description | One of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation. The presence of risk factors for hyperglycemia or hypertension can result in endothelial nitric oxide (eNOS) dysfunction, thereby causing oxidative stress and vasoconstriction of blood vessels. The renin angiotensin system is involved in the physiopathology of stroke and has an important impact on hypertension. This article targets the role of the renin angiotensin system specifically the inhibition of the angiotensin converting system in cardioprotection and neuroprotection. The mechanism of action of the renin-angiotensin-aldosterone system (RAAS) is observed through effects on AT1, AT2 and Mass receptors. The future relationship of cardiovascular disease and the renin-angiotensin system is full of possibilities, as new agonist molecules emerge as potential candidates to limit the impairments caused by cardiovascular disease. |
| format | Article |
| id | doaj-art-1eb1db934c814f62b632163ed0317935 |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-1eb1db934c814f62b632163ed03179352025-01-16T11:19:45ZengEDP SciencesBIO Web of Conferences2117-44582024-01-011480100610.1051/bioconf/202414801006bioconf_icobeaf2024_01006Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic reviewCapritasari Rafiastiana0Akrom1Setianto Arif Budi2Faculty of Health, Universitas Muhammadiyah Magelang, MagelangFaculty of Pharmacy, Universitas Ahmad Dahlan, YogyakartaFaculty of Pharmacy, Universitas Ahmad Dahlan, YogyakartaOne of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation. The presence of risk factors for hyperglycemia or hypertension can result in endothelial nitric oxide (eNOS) dysfunction, thereby causing oxidative stress and vasoconstriction of blood vessels. The renin angiotensin system is involved in the physiopathology of stroke and has an important impact on hypertension. This article targets the role of the renin angiotensin system specifically the inhibition of the angiotensin converting system in cardioprotection and neuroprotection. The mechanism of action of the renin-angiotensin-aldosterone system (RAAS) is observed through effects on AT1, AT2 and Mass receptors. The future relationship of cardiovascular disease and the renin-angiotensin system is full of possibilities, as new agonist molecules emerge as potential candidates to limit the impairments caused by cardiovascular disease.https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_01006.pdf |
| spellingShingle | Capritasari Rafiastiana Akrom Setianto Arif Budi Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review BIO Web of Conferences |
| title | Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review |
| title_full | Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review |
| title_fullStr | Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review |
| title_full_unstemmed | Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review |
| title_short | Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review |
| title_sort | cardio and neuro protection by renin angiotensin aldosterone system focus inhibition angiotensin converting enzyme a systematic review |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_01006.pdf |
| work_keys_str_mv | AT capritasarirafiastiana cardioandneuroprotectionbyreninangiotensinaldosteronesystemfocusinhibitionangiotensinconvertingenzymeasystematicreview AT akrom cardioandneuroprotectionbyreninangiotensinaldosteronesystemfocusinhibitionangiotensinconvertingenzymeasystematicreview AT setiantoarifbudi cardioandneuroprotectionbyreninangiotensinaldosteronesystemfocusinhibitionangiotensinconvertingenzymeasystematicreview |