An actin bracket-induced elastoplastic transition determines epithelial folding irreversibility

Abstract During morphogenesis, epithelial sheets undergo sequential folding to form three-dimensional organ structures. The resulting folds are often irreversible, ensuring that morphogenesis progresses in one direction. However, the mechanism establishing folding irreversibility remains unclear. He...

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Bibliographic Details
Main Authors: Aki Teranishi, Misato Mori, Rihoko Ichiki, Satoshi Toda, Go Shioi, Satoru Okuda
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54906-7
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