Tracing the Spectrum of Inborn Errors of Immunity from Past to Present
Human inborn errors of immunity (IEI) constitute a constellation of genetic disorders with profound implications for immune system function, leading to recurrent infections, immune dysregulations, and malignancies. The field of IEI has undergone a tremendous evolution over the course of seventy year...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2024-04-01
|
| Series: | Turkish Journal of Immunology |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tji&un=TJI-82787 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Human inborn errors of immunity (IEI) constitute a constellation of genetic disorders with profound implications for immune system function, leading to recurrent infections, immune dysregulations, and malignancies. The field of IEI has undergone a tremendous evolution over the course of seventy years, with substantial strides in comprehending the clinical and immunological aspects of monogenic disorders. Furthermore, these endeavors have synergized with innovative therapeutic modalities, forging a trajectory toward enhanced patient care. These advances promise to favorably transform the outcomes of many IEI to provide patients with increased life expectancy and improved quality of life. In this special issue of the Turkish Journal of Immunology, we will survey some recent advances in the field of IEI with a focus on disease pathogenesis and outcomes. |
|---|---|
| ISSN: | 1301-109X 2147-8325 |